Afatinib Intermediate Trans-4-Dimethylaminocrotonic acid hydrochloride CAS No.848133-35-7 CAS NO.848133-35-7

Alfaitinib is a potent and irreversible double inhibitor of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) tyrosine kinase, for treatment first-line advanced non-small cell lung cancer (NSCLC) and HER2-positive advanced brest cancer patients.

1) Production Capacity: 4000 kgs / month

2) GMP approved workshop to ensure quality

3) Quality Standard: BP Grade, USP Grade, EP Grade, CHP Grade 

4) Provide flexible quantity from 1 gram to 25 kg or more

5) Third party lab test such as SGS, BV, Internek

6) Flexible shipment: By courier FEDEX, DHL, UPS, TNT, EMS, by air or sea

7) Quality Control System: QC and QA system based on ISO quality manage system, whole control from raw material, production and finished product

8) Provide HPLC, MOA, ROS, COA and other information

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Afatinib Intermediate Trans-4-Dimethylaminocrotonic acid hydrochloride CAS No.848133-35-7

Product Name: Trans-4-Dimethylaminocrotonic acid hydrochloride 

Synonyms: (E)-4-(Dimethylamino)-2-butenoic acid hydrochloride;

trans-4-dimethylaminocrotonic acid HCl;

2-butenoic acid, 4-(dimethylamino)-, hydrochloride;

(E)-4-(dimethylamino)but-2-enoic acid hydrochloride;

4-DiMethylaMino-But-2-Enoic Acid Hcl Salt;

Afatinib intermediate;

(2E)-4-(diMethylaMino)but-2-enoic acid hydrochloride

CAS No.: 848133-35-7

Molecular Formula: C₆H₁₁NO₂^.HCl

Molecular Weight: 165.62

Molecular Structure: 

Specification & COA: Please contact us

Packing: 

Storage: Store in cool and dry palce. Keep away from strong light ,high temperature.

Henan Estar Biochem Technology Corporation Ltd is a comprehensive high-tech corporation, professional engaged in APIS,intermediates, fine chemicals and surfactant products R&D, manufacture, market and international trade in since Aug 08, 2003, has license for independent import and export business.

After more than 10 years of development and growth, Estar Biochem main manufacture and supply cardiovascular, hypoglycemic, hypolipidemic,anticoagulation, anticancer,anti-depression, anti-dementia and anti-asthma etc pharmaceutical intermediates ,mild surfactant.

Estar Biochem has four standard production workshop of pharmaceutical intermediates, glass enamel and stainless steel reaction still more than 50 sets capacity from 20L to 8000L, four sets advanced sulfonation and high tower spary powder equipment, and  fully equipped laboratory.